Model, simulate, and analyze biochemical systems
sing a single tool.

Harmony workshop 2017, June. 

New modeling textbook (Systems Biology: Introduction to Pathway Modeling)

Tellurium Tutorials YouTube Channel now Available.

Tellurium was updated on February 2017 to version 1.3.6

We have noticed unusual behavior with 1.3.5 and 1.3.6 where users have to type shift-return to enter commands at the IPython console. Apparently this is a bug upstream of spyder which will be fixed next month at which point we will release 1.3.7 that includes that fix. If you find the use of shift-return annoying we recommend you download 1.3.4 until 1.3.7 is released.

View source on GitHub.

Ready to install? Please visit the download page.

Go to the News page for update details


Tellurium (te.) is a Python environment based on spyder2 IDE. It combines a number of existing libraries, including libSBMLlibRoadRunner (including libStruct), libAntimony, and is extensible via telPlugins. In addition other tools kits such as matplotlib and NumPy are used to provide additional analysis and plotting support. On Windows, Tellurium comes with pip, so you can easily pip install package whenever you need a third-party package.


Jayit Biswas (Ratelaw database)
Kiri Choi (SEDML/COMBINE bindings, Spyder2 and Windows installer, Docs, Ratelaw database)
Wilbert Copeland (C API, Auto2000 debugging, refactoring libRoadrunner)
Caroline Cannistra (simpleSBML, libRoadRunner RK45, Docs)
Alex Darling (C API docs and testing)
Nasir Elmi (Stochastic test suite compliance)
Michal Galdzicki (Integrated suite, all-in-one installer, test suite);
Stanley Gu (SBML2Matlab and web interface);
Totte Karlsson (telPlugins, C# translation, C API, data fitting and bifurcation analysis);
Matthias König (SEDML, debugging, tutorial, libroadrunner, docs and Linux support)
Kyle Medley (Spyder2, Mac, libRoadRunner debugging and development, test suite, online build system, Docs, Network viewer)
Andy Somogyi (libRoadRunner Python API and C++ API, LLVM backend)
Lucian Smith (libAntimony, Python bindings, test suite)
Kaylene Stocking (Better plotting facilities, additional examples, Docs)
Herbert Sauro (PI,, Docs, testing)

Te. relies greatly on open source contributions from:
Frank Bergmann (libStruct, libSEDML);
Mike Hucka,  Sarah Keating (libSBML);
Pierre Raybaut (Spyder2, Winpython)

New contributions are always welcome.

The Tellurium and libRoadRunner project was funded from the NIH/NIGMS (GM081070).

All code is open source. Temporarily there is PyQt4 – GPL licensed code. Licences used include LGPL,  Apache 2, MIT, and New BDS.